000			04191cam a2200457 i 4500
001			20861424
003			BJBSDDR
005			20240401111100.0
007			ta
008			190221s2019 nyua b 001 0 eng
010			_a 2019007196
020			_a9781501191978 (hardback)
020			_a1501191977 (hardback)
040			_aDLC _beng _cDLC _erda _dDLC
041			_aeng
042			_apcc
050	1	4	_aQH 528.5 _bS616l 2019
082	0	0	_a570
100	1		_aSinclair, David A. _q(David Andrew), _d1969- _934785
245	1	0	_aLifespan : _bwhy we age--and why we don't have to / _cDavid A. Sinclair, PhD, AO, with Matthew D. LaPlante ; illustrations by Catherine L. Delphia.
250			_aFirst Atria Books hardcover edition.
264		1	_aNew York : _bAtria Books, _c2019.
300			_axxiii, 406 pages : _billustrations ; _c24 cm.
336			_atext _btxt _2rdacontent
337			_aunmediated _bn _2rdamedia
338			_avolume _bnc _2rdacarrier
504			_aIncludes bibliographical references (pages 315-367) and index.
505	0		_aIntroduction: A grandmother's prayer What we know (the past). Viva Primordium ; The demented pianist ; The blind epidemic What we're learning (the present). Longevity now ; A better pill to swallow ; Big steps ahead ; The age of innovation Where we're going (the future). The shape of things to come ; A path forward Conclusion
520			_a"From an acclaimed Harvard professor and one of Time's most influential people, this paradigm-shifting book shows how almost everything we think we know about aging is wrong, offers a front-row seat to the amazing global effort to slow, stop, and reverse aging, and calls readers to consider a future where aging can be treated. For decades, experts have believed that we are at the mercy of our genes, and that natural damage to our genes--the kind that inevitably happens as we get older--makes us become sick and grow old. But what if everything you think you know about aging is wrong? What if aging is a disease--and that disease is treatable? In Lifespan, one of the world's foremost experts on aging and genetics reveals a groundbreaking new theory that will forever change the way we think about why we age and what we can do about it. Aging isn't immutable; we can have far more control over it than we realize. This eye-opening and provocative work takes us to the frontlines of research that is pushing the boundaries on our perceived scientific limitations, revealing incredible breakthroughs--many from Dr. David Sinclair's own lab--that demonstrate how we can slow down, or even reverse, the genetic clock. The key is activating newly discovered vitality genes--the decedents of an ancient survival circuit that is both the cause of aging and the key to reversing it. Dr. Sinclair shares the emerging technologies and simple lifestyle changes--such as intermittent fasting, cold exposure, and exercising with the right intensity--that have been shown to help lead to longer lives. Lifespan provides a roadmap for taking charge of our own health destiny and a bold new vision for the future when humankind is able to live to be 100 years young"-- _cProvided by publisher.
520			_a"From an acclaimed Harvard professor and one of Time's most influential people, this paradigm-shifting book shows how almost everything we think we know about aging is wrong, offers a front-row seat to the amazing global effort to slow, stop, and reverse aging, and calls readers to consider a future where aging can be treated"-- _cProvided by publisher.
650		0	_aLife spans (Biology)
650		0	_aLongevity.
650		4	_aEsperanza de vida (Biología) _934960
650		4	_aLongevidad. _91894
700	1		_aLaPlante, Matthew D. _95761
776	0	8	_iOnline version: _aSinclair, David A., 1969- author. _tLifespan _bFirst Atria Books hardcover edition. _dNew York : Atria Books, 2019 _z9781501191992 _w(DLC) 2019009229
906			_a7 _bcbc _corignew _d1 _eecip _f20 _gy-gencatlg
942			_2lcc _cBK
946			_isba
999			_c120851 _d120851